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It may be pointed out here that earlier reports are available in literature which have demonstrated the enzyme-catalysed formation of dityrosine from tyrosine 7

The backbone orientations of all the conformers are schematically depicted in Supplementary Information, Figure S4

DNA fragments of ER-shRNA#30, ER-shRNA#98, SLC7A11-shRNA#3, SLC7A11-shRNA#24, SLC3A2-shRNA#86 and SLC3A2-shRNA#87 (sequences from Sigma-Aldrich website) were subcloned into the Eco R I and Age I digested pLKO.1 vector, respectively