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doi: 10.1146/annurev-pharmtox-010818-021041

Clozapine-induced reduction of L-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice

1 Introduction Fatigue is a common chronic cross-diagnostic symptom ( In CFS, fatigue of unknown origin is a hallmark diagnostic feature ( In hypothyroidism, about 15 20% of patients report fatigue or brain fog even after correction of thyroxine levels to normal with levothyroxine ( L-carnitine supplementation has been suggested to reduce fatigue in both hypothyroidism (30, 31)

Guizhou Province Excellent Youth Science and Technology Talent Project: Qiankehe Platform Talent [2021] No