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demonstrated that 60.6% of children with new onset diabetes were positive for autoantibodies directed towards deamidated IA-2ec compared to 19.3% positive to the wild type IA-2ec, while only 14.2% of adults with T1D and 4.1% of patients with Latent autoimmune diabetes of adults (LADA) showed autoantibodies towards deamidated IA-2 compared to 8.8% and 1.5% to the wild type IA-2ec, respectively (126)

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Front Pharmacol 9:722 Liang Z, Lippman SM, Kawabe A, Shimada Y, Xu XC (2003) Identification of benzo(a)pyrene diol epoxide-binding DNA fragments using DNA immunoprecipitation technique