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Transcobalamin proteins then carry B12 in the blood plasma to be used by the body

Excitatory stimulation of NMDA receptors on adult hippocampal NSCs result in elevated intracellular calcium and activation of the proneural gene, NeuroD1, highlighting direct effects of glutamate on adult neuroprogenitor cells [115]

The dosing itself does not change, but the monitoring requirements are more stringent
