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125,157 Diagnostic approaches include pupillometry for objectively measuring pupil size and reactivity, pharmacological testing to assess responses to agents like pilocarpine, and dynamic pupillometry as a non-invasive biomarker for autonomic dysfunction

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These molecules bind to MET on hepatocytes via a paracrine pathway and through the peripheral blood circulation

Each of these dysfunctional synaptic-related functions due to oxidatively modified key proteins is observed in AD and MCI brains, and we propose that these oxidatively modified proteins contribute to the cognitive dysfunction and related clinical observations in AD and MCI