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CAMS Innovation Fund for Medical Sciences (2020-12M-5-001)
Brain Fog, Memory, and Mental Sharpness Brain fog refers to mental fatigue, difficulty concentrating, and memory lapses
Proteasome inhibition prevents further degradation of newly formed oxidized proteins and increases protein aggregation formation in cells (Takalo et al., 2013
The binding of IL-1 and TNF- to the TLR4 receptor initiates a signaling cascade involving multiple proteins and ultimately activates NF-B, which drives the expression of pro-inflammatory cytokines (140)
