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To complement the Jadad score, the Cochrane Risk of Bias Tool (RoB 2) (Sterne et al., 2019) was also used for RCTs to provide a domain-based qualitative evaluation, assessing risks related to selection, performance, detection, attrition, and reporting

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10.1021/acs.jmedchem.7b01422 8 BachD.-H.KimD.BaeS

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The results have been consistently promising, showing accelerated regeneration and improved functional outcomes with minimal adverse effects

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Pros of a Systemic Approach: Ease of Administration: It's incredibly simple, quick, and requires minimal technical skill

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