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Down-regulation of VGF impairs biogenesis of glucagon granules and suppresses glucagon hypersecretion To further elucidate the role of VGF in glucagon hypersecretion, we employed adenovirus-mediated shRNA targeting Vgf (Supplementary Fig

In this study, Xanthakos, senior author Heidi Kalkwarf, PhD, RD and their surgical colleagues, including Michael Helmrath, MD at Cincinnati Childrens and Thomas Inge, MD, PhD at Childrens Hospital Colorado, focused on the nutritional impacts of the two most common forms of the surgery: Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG)