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By inhibiting NNMTs consumption of SAM, 5-Amino-1MQ may affect the methylation status of various cellular targets

[DOI] [PubMed] [Google Scholar] 12.Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB
[DOI] [PubMed] [Google Scholar] 31.Guse AH, da Silva CP, Berg I, Skapenko AL, Weber K, Heyer P, et al

This indicates that inhibiting CD38 activity may have a role in the development of Alzheimers disease, although further studies are necessary
