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These effective combination therapies revealed the inherent susceptibility of TNBC to ferroptosis and highlighted the potential strategy of ferroptosis as a drug target of TNBC
453,454 Ferulic acid can improve the survival rate of copper-overloaded cells, significantly increase the expressions of SIRT1, Nrf2, SLC7A11, and GPX4, and downregulate the levels of MDA, 4-HNE and ROS
Evidence (chemotherapy and prophylactic cranial radiation therapy): Protocols of the former Pediatric Oncology Group (POG) treated children with T-ALL differently from children with B-ALL
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