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Although the administration of vitamin D in isolation did not yield improvements in muscle strength, both RT cohorts (regardless of vitamin D supplementation) exhibited marked enhancements in both upper and lower body strength and power

The SUMO protein (11 kDa) is involved in post-translational modification in eukaryotic cells, enhances solubility and stability of the binding partner when fused to the N-terminal (Marblestone et al., 2006), and allows simultaneous cleavage as it is recognized by the SUMO protease ( Saccharomyces cerevisiae Ulp1) at the conserved dipeptide glycineglycine (Li and Hochstrasser, 1999)

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They affect amyloidosis through their role in the synthesis and disposal of A, as well as through interactions with other CNS cells (Liddelow et al., 2017