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Two subgroups of cytosolic GSTs have been characterized based upon their interaction with glutathione: the Y-GST group, which uses a tyrosine residue to activate glutathione, and the S/C-GST, which instead uses serine or cysteine residues

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The people targeted for long-acting pre-exposure prophylaxis (PrEP) are those at high risk of HIV infection, in particular men who have sex with men ( M S M ) and transgender women