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81 If a patient has typical symptoms of IC/BPS (e.g., frequent urination driven by pain that increases with bladder filling and improves after voiding), then the clinician will begin treatment after excluding alternate disorders

Active compounds, such as astragaloside IV, attenuate diabetes-related activation of protein kinase B (Akt)/mammalian target of rapamycin (mTOR), NF-B, and extracellular signal-regulated kinases 1 and 2 (Erk1/2) signaling pathways, thereby decreasing podocyte apoptosis and albuminuria in preclinical models (135)

Figure 2 shows the relation between Device Profiles and Electronic Data Sheets