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Further data processing analysis for both platforms, including clustering, visualization, marker identification, differential expression analysis, and pathway enrichment were performed using the Seurat v5.0.3 99 , DElegate v1.2.1 100 , escape v2.5.5 101 , decoupleR v 2.14 69 , and UCell v2.12 102 packages in R Studio

doi: 10.1039/d2fo03677k 61 ShaJ.LiuZ.YuH.HuoX.WangJ.DuanY.et al