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Alston CL, et al

Pharmacological treatments are reserved for specific circumstances and limited to licensed medications with demonstrated efficacy and safety profiles, such as orlistat or semaglutide (NICE TA875)

Most of the time, if any reaction occurs, its due to how depleted your body is or how quickly your system adjusts to the boost

18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms