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In naturally aged rat ovaries, abnormal upregulation of transferrin (TF) and iron regulatory protein 2 (IRP2)-mediated transferrin receptor 1 (TfR1) leads to iron accumulation (Sze et al., 2022)
doi: 10.1021/acs.molpharmaceut.0c00048
In our prior work, we operationalized this distinction by measuring plasma CRP, IL-6, IL-8, TNF-, D-dimer, troponin I, and cortisol in patients with prediabetes (n = 26) and T2DM (n = 63)
