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Description
For maximum benefit, treatment with silymarin should be initiated as early as possible in patients with fatty liver disease and other distinct liver disease manifestations such as acute liver failure, when the regenerative potential of the liver is still high and when removal of oxidative stress, the cause of cytotoxicity, can achieve the best results

doi:10.3389/fcell.2021.804049 169

Plus, Section 503A allows for exemptions

doi: 10.1038/s12276-023-00971-9 36 GaoPTchernyshyovIChangT-CLeeY-SKitaKOchiTet al
