glutathione glutathione peroxidase 4: a new player in neurodegeneration? Glutathione Peroxidase Enzyme Molecule Poster
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On one hand, ROS can directly induce damage to mtDNA damage by oxidative modification of mtDNA bases

doi: 10.1016/j.msard.2023.105364 69 GiovannoniG.PopescuV.WuerfelJ.HellwigK.IacobaeusE.JensenM

10.1002/ajh.25103 3 BigotK.GondouinP.BenardR.MontagneP.YoualeJ.PiazzaM.et al (2020)

Superoxide dismutase ameliorates oxidative stress and regulates liver transcriptomics to provide therapeutic benefits in hepatic inflammation
