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For instance, several studies on a smaller number of patients showed higher IGF-1 levels in hypertensive patients compared to normotensive subjects (184187), whereas several cross-sectional studies indicated a neutral relationship between blood pressure and IGF-1 (52, 134, 188190)

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doi: 10.1183/09059180.00003609 9 JulioDAntuniMDPeterJ

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The dysregulation of ROS and GSH balance can tip the scales toward an oxidatively stressed microenvironment, contributing to the transformation and survival of cancerous cells

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