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Human aging Pilot study part 1: Voxel-based analysis on the hippocampal circuit Voxel-based analysis ( Figures 4B,C ) was performed by first transforming the non-contrast images using a diffeomorphic registration algorithm (Avants et al., 2009) with nearest-neighbor interpolation to an unbiased brain template created from the 177 scans in the Aging study (Avants et al., 2009)

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