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If you develop severe nausea taking both, you won't know which one caused it, and you may discontinue an effective medication unnecessarily

This occurs most commonly in idiopathic inflammatory myopathy, where ILD precedes myopathy symptoms and signs in 7.2% to 37.5% of patients (Hallowell and Paik, 2021)

Cross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells

Substance use disorder (especially alcoholism)
