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Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract Curr Pharm Des , 2018
So, artificially prolonging half-life through the use of a sustained-release formulation is another strategy to reduce drug adverse effects

[DOI] [PubMed] [Google Scholar] 109

This posits that even though Fragment 176-191 may not directly activate beta-3 adrenergic receptors, the increased number of receptors might amplify the natural lipolytic response to endogenous catecholamines (like adrenaline), which are suggested to engage these receptors directly
