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In addition to Parkinson's disease, disturbed Mn homeostasis has been observed in various other neurodegenerative diseases and mental conditions
These scenarios illustrate how multigene profiles can refine initial drug choice (e.g., avoiding primary CYP-substrates in extremes of metabolism), starting dose, titration speed, and monitoring intensity

Hu H, Xia SH, Li AD, Xu X, Cai Y, Han YL et al
