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Later on, this was proved in the OVX mouse model that showed GM dysbiosis due to estrogen deficiency brought about by integral bone loss through enhanced gut permeability alongside excessive expression of cytokines, which orchestrated osteoclastogenesis

Statistics on the percentage of the older population (65 years and above) showed an increase in this age group every year, from 6.7% in 2019 to 7.0% in 2020, and is estimated to reach 15% by 2030, thus marking Malaysia as an ageing nation

However, caution needs to be taken when increasing the intake of any of the lipid soluble vitamins

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