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Unexpectedly, tumor burden was significantly reduced in mice with NOS2-deficient bone marrow chimers compared to the wild-type mice, suggesting that even though the number of M2 macrophages in iNOS-deficient TME is not affected, the immunosuppressive function of M2 macrophages may change
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A study of 240 Chinese women found that clinical symptoms of women in the BV arm ( N = 180) significantly improved following topical treatment with berberine and the Nugent score improved in 92.78% (117)
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