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Therapeutic drug monitoring of antidepressants: an underused but potentially valuable tool in primary care
Then, the rate-limiting enzyme in arginine synthesis, argininosuccinate synthetase 1 (ASS1), catalyzes the conversion of citrulline and aspartate into argininosuccinate, which is then cleaved into arginine and fumarate by argininosuccinate lyase (ASL) (Figure 1)
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Gadolinium is effectively driven out of the chelate, potentially quite rapidly
