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21 Heriditary cystatin C amyloid angiopathy (HCCAA): Hereditary cystatin C amyloid angiopathy (HCCAA) is a rare dominantly inherited disease caused by a leucine to glutamine variant of human cystatin C (hCC)

The anti-inflammatory, antioxidant, and immunomodulatory properties of MSCs have shown promise in ameliorating PCOS, primarily through the secretion of bioactive factors or by direct cell-to-cell interactions

Furthermore, different forms of selenium compounds influence the structure of the microbiota by altering their metabolic activity

Where serum B12 results are borderline or do not fit the clinical picture, further tests such as active B12 (holotranscobalamin), methylmalonic acid, or homocysteine may be helpful