glutathione redoxin redox cycle. In the schematic diagram are represented the Regulation of the redox homeostasis
Description
Resistance mechanisms and adaptation to therapeutic stress CSCs possess a diverse array of intrinsic and extrinsic resistance mechanisms that enable them to withstand chemotherapy, radiation, and targeted therapies
134 By inhibiting cell proliferation and cladogenesis, DHPO exhibits significant antitumor activity in vitro and in vivo

It is supplemented in its free taurine form, which is water-soluble and readily absorbed by fish

Finally, in phase III, the conjugated xenobiotics may be further processed, before being recognised by efflux transporters and pumped out of cells
