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Vitamin C reconfigures the gut microbiota, improves the intestinal environment, reduces inflammatory responses and oxidative stress in the paraventricular nucleus of the hypothalamus, thereby weakening sympathetic nervous activity in hypertensive rats and lowering blood pressure (83)

Furthermore, GHK-Cu helps restore the natural skin barrier, clarity, and attractiveness by promoting the regeneration of healthy skin cells and decreasing dead skin cells (1)

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Central Sensitization Central sensitization, defined by the IASP as increased responsiveness of nociceptive neurons in the CNS to their normal or subthreshold afferent input [53], represents a fundamental form of synaptic plasticity that underlies chronic pain hypersensitivity (Figure 2)