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If severe B12 deficiency with neurological involvement is suspected, treatment should be initiated promptly without waiting for test results, and specialist advice may be needed
In particular, CD38 may have a role not only in the regulation of intracellular but also extracellular NAD, and may modulate the availability on extracellular applied NAD in some cellular systems
doi: 10.3389/fbioe.2022.983872
Lipid-based vehicles penetrate significantly better than water-based serums
