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and (ii) delivery-related issues, as PLGA nanoparticles require further engineering to achieve high selectivity and specificity, overcome BBB restrictions, and effectively target pathological sites, and/or multi-targeting strategies may be necessary as AD exhibits multiple pathological targets (Lu et al., 2023)
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Specifically, vitamin B12 helps us metabolize food, produce red blood cells, and methylate DNA (more on this later)
Reported side effects have mostly been mild: transient injection-site reactions, occasional headaches, or mild flu-like symptoms
