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After the clearance of pathogens, the majority of effector T cells die through apoptosis and the remaining memory T (T mem ) cells are responsible for immunity upon re-exposure to the same pathogen

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Notably, p53 activates PCDHB14 and inhibits SLC7A11 expression by enhancing p65 protein ubiquitination-mediated degradation, thereby abrogating p65 bind to the SLC7A11 promoter (Zhao et al., 2022)