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The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )
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Interestingly, at the end of a three-month follow-up, although both groups showed significant improvements in pain assessed by VAS, the change in the B12 arm was significantly greater relative to the nortriptyline group
These two forms of B12 have the same effects but have their own different strengths in different situations
