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This endotoxemia triggers the activation of the nuclear factor-B (NF-B) pathway and upregulates the expression of IL-6 and TNF- , thereby exacerbating inflammation associated with asthma

2021;28(765775):e765
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After sedation with 2 Vol% isoflurane, the mice were placed on a heated plate with constant heart rate, respiratory rate and body temperature monitoring via a rectal probe

Therefore, almost all risk factors that can cause primary hypertension can increase the incidence of ED, and likewise, ED can serve as an antecedent predictor of early cardiovascular events (44, 45)
