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Lipids, in particular cholesterol (Habchi et al., 2018) and gangliosides (Matsuzaki, 2020), can promote the primary nucleation of A, an event that at the normal A brain concentrations is otherwise likely to be rare (Habchi et al., 2018)

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[DOI] [PubMed] [Google Scholar] 99.Calabrese V, Ravagna A, Colombrita C, Scapagnini G, Guagliano E, Calvani M, Butterfield DA, Giuffrida Stella AM

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The net result of this activation process is the consumption of two molar equivalents of ATP

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