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Journal of Cosmetic Dermatology , 15(3), 253-261

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Additionally, AS-IV restored dopaminergic neurons and alleviated PD-associated motor function decline in mice with chemically induced PD, revealing a potential PD therapeutic candidate with senolytic benefits
VEGF also promotes the expression of PD-1 in tumor cells, which leads to T cell exhaustion and ultimately destroys the anti-tumor immune response, resulting in immune cell inhibition (186)
