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doi: 10.3390/biomedicines13061464 29 BrownT

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Zhang L., Wang X., Cueto R., Effi C., Zhang Y., Tan H., Qin X., Ji Y., Yang X., Wang H
J Clin Endocrinol Metab 42:296, 1976

The logic is that local administration creates higher peptide concentrations at the relevant tissue
