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Description
An additional clinically significant group of enzymes that requires tetrahydrobiopterin as cofactor are the nitric oxide synthase (NOS) family of enzymes
In conclusion, the study provides evidence that EGCG can reverse epigenetic silencing of RXR by reducing promoter methylation
With recent improvements in genome engineering, we will be able to assess the effects of small modifications to RARs/RXRs encoding genes on thyroid hormonal pathways
Cell 2011
