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These findings clearly show that GPX1 is irreplaceable by other selenoproteins in protecting against systemic oxidative stress, and GPX1 has a significant antioxidant function in the body ( FIGURE 1 On the surface, the mice after GPX1 KO performed normally, but these mice were susceptible to the production of oxidative substances, and when stimulated, they were easy to cause harm to mice and increase oxidative stress in vivo

Acknowledgements I gratefully acknowledge the help of Fusheng Zhang who have helped me wrote the figures

performed a prospective, controlled study of fluoxetine or sertraline initiation in 28 patients with major depression and hypothyroidism and 29 patients with major depression and normal thyroid function

Glutathione is often called the bodys master antioxidant because it helps neutralise free radicals and reduce oxidative stress