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81 In an abstract of the 2022 Society of Gynecologic Oncology (SGO) Annual Meeting, Borden and colleagues described a retrospective study of 18 recurrent EC treated with single-agent pembrolizumab, and found that that recurrence-free survival and OS was significantly decreased in patients with epigenetic MMR-D (n=12)

Cancer 14 , 153167 (2007)

Basically, the translocation of MOTS-c from the mitochondria to the nucleus turns off the coenzyme that wants to store sugar creating a state of fat burning while also encouraging healthy mitochondria turnover

Antioxidants play a vital role in protecting cells from damage from free radicals that are linked to cancer, heart disease, and other conditions [58]