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[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Wind J, Versteegt J, Twisk J, van der Werf TS, Bindels AJ, Spijkstra JJ, Girbes AR, Groeneveld AB
doi: 10.3390/cells9102308
202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione
"None of them are proven," said Dr
