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This analysis revealed a downregulation of the hypoxia regulon and upregulation of the TGF- regulon in GPX2 KO cells as the most significantly deregulated pathways (Fig

Ajani JA, Faust J, Yao J, Komaki R, Stevens C, Swisher S, Putnam JB, Vaporciyan A, Smythe R, Walsh G, Rice D, Roth J
, Chmiel, C

However, a PTHrP 134 maintains a less pronounced anabolic effect to the bone and osteoblasts possibly due its higher clearance rate [52, 53]
