5-amino-1mq mechanism of action nnmt inhibitor Emerging opportunities for nicotinamide N-methyltransferase (NNMT) clinical translation 5-Amino-1MQ – 50mg (Nicotinamide N-Methyltransferase
Description
There are often large gaps between total B12 and active-B12 levels in the blood

Cell Immunol

A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss

Aplastic anemia and hypoplastic anemia are known to occur after chloramphenicol administration