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The US Food and Drug Administration (FDA) has approved giving L-carnitine intravenously (by IV) but not by mouth to treat and prevent L-carnitine deficiency in these patients
TDP-43 activates microglia through NF-B and NLRP3 inflammasome

FUMA was used to annotate the genome-wide significant (GWS) risk loci ( p 0.0625) were identified, and one sample from each related pair was excluded 75
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