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In addition, catalase (CAT) enzyme levels were measured following the procedures of Aebi (1984), and reduced glutathione (GSH) estimations were made via the protocol described by Beutler et al

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They are readily oxidized to the corresponding o -quinones, which in turn are converted to GSH adducts (Monks and Lau, 1994, Wan and OBrien, 2014)

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Future trial designs should systematically take these things into account

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