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From a structural perspective, luteolin is defined by the presence of two benzene rings (A and B) interconnected by a heterocyclic pyrone ring (C), thereby establishing the characteristic C6C3C6 backbone that is emblematic of flavonoids ( 2.2 Natural dietary sources Luteolin is extensively found in traditional herbal remedies and nutritional supplements

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Moreover, majority of Countries let herbal products into the market without a proper scientific review or the necessary safety and toxicological research, manufacturing procedures and quality standards are also not effectively regulated [26]

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