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Bennett MH, Feldmeier J, Hampson NB, Smee R, Milross C

182 In two subsequent studies, low-dose curcumin showed a non-significant trend toward lowering total cholesterol and LDL cholesterol in acute coronary patients, 183 while high dose-curcumin (14 grams/day) exhibited non-significant increases in total-, LDL-, and HDL cholesterol

To facilitate further high-throughput annotation of oxGPLs, we compiled our results obtained by MS3 and elevated energy stepped HCD MS2 fragmentation of selected oxylipin standards and in vitro oxidized PC lipids (Supplementary Data 1.1 and 1.2), literature data on the fragmentation of oxidized free fatty acids and complex lipids 20,22,26,27,28,29,30,31,32,33,34 , as well as available MS2 spectra from METLIN, LIPID MAPS, and MS DIAL.msp library, in the form of fragmentation rules exemplified here for different modification types and positions on oxidized oleoyl (18:1), linoleoyl (18:2), and arachidonoyl (20:4) chains in PC lipids (Supplementary Data 2)

Bleeding, swelling, and bruising are minimal