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Currently, targeted neuroprotective drugs acting on ferroptosis pathways are under progressive development, with iron chelators, antioxidants, and free radical scavengers being extensively investigated to achieve neuronal protection through modulation of ferroptosis processes (224)

Mol Pharmacol 65:5507, PMID: 14978233 Coles BF, Kadlubar FF (2003) Detoxification of electrophilic compounds by glutathione S -transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs

Clooney, who is the director, producer and star of the film, claimed that he had contributed in writing "all but two scenes" of it, and requested a writing credit alongside Duncan Brantley and Rick Reilly, who had worked on the screenplay for 17 years

They serve a key function in regulating gene expression by either limiting protein translation or increasing the breakdown of mRNA molecules (Croce and Calin 2005)