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We found no difference in the expression of MBP or MOG with treatment of slices with CPZ alone or CPZ + rapamycin, suggesting rapamycin had no further effect on the demyelination produced with CPZ treatment alone

drafted the Introduction, Molecular Pathways, and Conclusion sections, prepared Figure 1, and integrated all sections of the manuscript

the evidence for this is more extensive in human medicine, but is not as well established in horses

TGM2 normally occurs in an inactive, closed conformation but is rapidly converted to the open, active form by injury (Griffin et al., 2002
