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The tesofensine plus 5-HTP/CB combination does not result in synergistic interaction in a sucrose intake suppression assay The anorexigenic effects of tesofensine, 5-HTP/CB and 1:1 and 3:1 combinations of individual components were assayed by the consumption of sucrose

doi: 10.1186/s12875-024-02540-z

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It's possible that AOD9604 may influence the fat cells and lipolytic receptors, particularly given its observed association with changes in weight and fat in murine models